1,1-Bis(hydroxymethyl)cyclopropane is an organic compound with the formula $$ C_5H_{10}O_2 $$ and a molecular weight of 102.13 g/mol. It is a clear, colorless liquid, though its boiling point is not specified. This compound has two hydroxymethyl groups attached to a cyclopropane ring, giving it unique structural properties. It is made by hydrogenating 1,1-cyclopropanedicarboxylic esters using metal catalysts. It is recognized as a reactive intermediate in many chemical reactions and acts as a valuable building block in organic formation. Industries that utilize 1,1-bis(hydroxymethyl)cyclopropane include the pharmaceutical industry where it serves as a key intermediate in the synthesis of montelukast sodium, a leukotriene antagonist used for asthma treatment. Additionally, it plays a role in chemical manufacturing, particularly in the production of morphine alkaloids and as an inhibitor of 5-lipoxygenase, contributing to various chemical processes. Furthermore, the compound is valuable in organic synthesis where its unique structure allows for the creation of different organic compounds, showcasing its adaptability in a range of chemical reactions.
Applications:
1.Making Montelukast Sodium: Used as an important ingredient in producing montelukast sodium which is a medication for asthma.
2.Creating Morphine Alkaloids: Helps in making different morphine related compounds, supporting pharmaceutical research.
3.Blocking 5-Lipoxygenase: Works as a blocker of 5-lipoxygenase which is involved in inflammation.
4.Used in Organic Chemistry: Its two hydroxymethyl groups make it more reactive, making it useful in many organic chemical processes.